Hypothesis-based weight-of-evidence evaluation of the human carcinogenicity of toluene diisocyanate.

Prueitt, Robyn L; Rhomberg, Lorenz R; Goodman, Julie E

Prueitt, Robyn L; Rhomberg, Lorenz R; Goodman, Julie E.

Affiliation

Prueitt RL; Gradient, Cambridge, MA, USA. jgoodman@gradientcorp.com

Crit Rev Toxicol ; 43(5): 391-435, 2013 May.

Article in En | MEDLINE | ID: mdl-23675773

Subject(s)

Carcinogens/toxicity; Neoplasms/chemically induced; Toluene 2,4-Diisocyanate/toxicity; Administration, Oral; Animals; Carcinogens/administration & dosage; Carcinogens/metabolism; Humans; Inhalation Exposure/adverse effects; Mice; Neoplasms/epidemiology; Neoplasms/pathology; Occupational Exposure/adverse effects; Phenylenediamines/toxicity; Rats; Species Specificity; Toluene 2,4-Diisocyanate/administration & dosage; Toluene 2,4-Diisocyanate/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinogens / Toluene 2,4-Diisocyanate / Neoplasms Limits: Animals / Humans Language: En Journal: Crit Rev Toxicol Journal subject: TOXICOLOGIA Year: 2013 Type: Article Affiliation country: United States

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