Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties.
Int J Biochem Cell Biol
; 45(8): 1701-9, 2013 Aug.
Article
in En
| MEDLINE
| ID: mdl-23707200
Key words
1,2-dipalmitoyl-sn-glycero-3-phosphocholine; 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol; 3-NO(2)-Tyr; 3-nitro-tyrosine; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; 7-amino-4-methyl coumarin; AEBSF; AMC; Abz; Antimicrobial protein; BALF; BCA; CA-074; CF; Cat; Collectin; Cysteine protease; Cystic fibrosis; DL-dithiothreitol; DPPC; DPPG; DTT; E-64; FRET; HNE; L-3-carboxy-trans-2.3-epoxypropionyl-leucylamido-(4-guanidino) butane; Lung; MMTs; Mu-Leu-Hph-VSPh; N-(l-3-trans-propylcarbamoyloxirane-2-carbonyl)-l-isoleucyl-l-proline; NSP; P. aeruginosa-negative; PMA; PMSF; Proteolysis; Ps+; Ps-; Pseudomonas aeruginosa-positive; RT; SP-A; TBS; Z; benzyloxycarbonyl; bicinchoninic acid; broncho-alveolar lavage fluid; cathepsin; cystic fibrosis; fluorescence resonance energy transfer; human neutrophil elastase; methylmethanethiosulfonate; morpholine urea-leucyl-homophenylalanyl-(vinylsulfonyl)benzene; neutrophil serine protease; ortho-aminobenzoic acid; phenylmethylsulfonyl fluoride; phorbol 12-myristate 13-acetate; room temperature; surfactant protein A; tris buffer saline
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cathepsins
/
Pulmonary Surfactant-Associated Protein A
/
Lung
/
Anti-Bacterial Agents
Limits:
Animals
/
Humans
Language:
En
Journal:
Int J Biochem Cell Biol
Journal subject:
BIOQUIMICA
Year:
2013
Type:
Article
Affiliation country:
France