Hyperoxia causes reduced density of retinal astrocytes in the central avascular zone in the mouse model of oxygen-induced retinopathy.

Bucher, Felicitas; Stahl, Andreas; Agostini, Hansjürgen T; Martin, Gottfried

Bucher, Felicitas; Stahl, Andreas; Agostini, Hansjürgen T; Martin, Gottfried.

Affiliation

Bucher F; Augenklinik, Universitätsklinikum Freiburg, Killianstr. 5, 79106 Freiburg, Germany.

Mol Cell Neurosci ; 56: 225-33, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23756201

Subject(s)

Astrocytes/metabolism; Hyperoxia/complications; Neovascularization, Pathologic; Retina/pathology; Retinopathy of Prematurity/pathology; Animals; Astrocytes/pathology; Caspase 3/genetics; Caspase 3/metabolism; Collagen Type IV/genetics; Collagen Type IV/metabolism; Desmin/genetics; Desmin/metabolism; Glial Fibrillary Acidic Protein/genetics; Glial Fibrillary Acidic Protein/metabolism; Glutamate-Ammonia Ligase/genetics; Glutamate-Ammonia Ligase/metabolism; Histones/genetics; Histones/metabolism; Hyperoxia/metabolism; Hyperoxia/pathology; Ki-67 Antigen/genetics; Ki-67 Antigen/metabolism; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Oxygen/toxicity; PAX2 Transcription Factor/genetics; PAX2 Transcription Factor/metabolism; Retina/metabolism; Retinopathy of Prematurity/etiology; Retinopathy of Prematurity/metabolism

Key words

Angiogenesis; Green fluorescent protein; Immunohistochemistry; Neovascularization; Transgenic mice

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / Retinopathy of Prematurity / Astrocytes / Hyperoxia / Neovascularization, Pathologic Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2013 Type: Article Affiliation country: Germany

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