HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization.

Herjan, Tomasz; Yao, Peng; Qian, Wen; Li, Xiao; Liu, Caini; Bulek, Katarzyna; Sun, Dongxu; Yang, Wen-Pin; Zhu, Jun; He, Aiqing; Carman, Julie A; Erzurum, Serpil C; Lipshitz, Howard D; Fox, Paul L; Hamilton, Thomas A; Li, Xiaoxia

Herjan, Tomasz; Yao, Peng; Qian, Wen; Li, Xiao; Liu, Caini; Bulek, Katarzyna; Sun, Dongxu; Yang, Wen-Pin; Zhu, Jun; He, Aiqing; Carman, Julie A; Erzurum, Serpil C; Lipshitz, Howard D; Fox, Paul L; Hamilton, Thomas A; Li, Xiaoxia.

Affiliation

Herjan T; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

J Immunol ; 191(2): 640-9, 2013 Jul 15.

Article in En | MEDLINE | ID: mdl-23772036

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Chemokine CXCL1/genetics; Chemokine CXCL5/genetics; ELAV Proteins/metabolism; Interleukin-17/metabolism; RNA Stability; Animals; Cell Line; ELAV Proteins/genetics; HeLa Cells; Humans; Inflammation/immunology; Lung/metabolism; Mice; Mice, Knockout; Protein Binding; RNA, Messenger/metabolism; Respiratory Mucosa/metabolism; Signal Transduction; Ubiquitination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-17 / RNA Stability / Adaptor Proteins, Signal Transducing / ELAV Proteins / Chemokine CXCL1 / Chemokine CXCL5 Limits: Animals / Humans Language: En Journal: J Immunol Year: 2013 Type: Article Affiliation country: United States

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