[Non-invasive diagnosis bladder cancer: new molecular markers and future perspectives]. / Diagnóstico no invasivo en cáncer de vejiga: nuevos marcadores moleculares y futuras perspectivas.
Arch Esp Urol
; 66(5): 487-94, 2013 Jun.
Article
in Es
| MEDLINE
| ID: mdl-23793766
ABSTRACT
Bladder cancer represents a very important entity in the field of urologic oncology. At the time of diagnosis 70% of them are non muscle-invasive tumors with a very variable risk of recurrence and progression. These patients will require a periodic follow up, at least for 5 years, performing multiple cystoscopies and urine cytologies throughout their lifes. These diagnostic tests are either invasive or have a low sensitivity, a fact that has stimulated the search of non-invasive markers with high sensitivity for the diagnosis of bladder cancer. The great advantage in this neoplasia is the availability of a biologic sample such as urine, which being in close contact with the urothelium collects exfoliated cells, representing a valuable non invasive tool for the diagnosis and follow up of this neoplasias. In this article we try to perform a review of those markers for bladder cancer already marketed and under development, as well as future diagnostic perspectives.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Urinary Bladder Neoplasms
/
Biomarkers
Type of study:
Diagnostic_studies
Limits:
Animals
/
Humans
Language:
Es
Journal:
Arch Esp Urol
Year:
2013
Type:
Article