Dioxolanes/pharmacology; Glioblastoma/enzymology; Glioblastoma/pathology; JNK Mitogen-Activated Protein Kinases/metabolism; Reactive Oxygen Species/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism; Astrocytes/drug effects; Astrocytes/pathology; Cell Death/drug effects; Cell Line, Tumor; Dioxolanes/chemistry; Drug Screening Assays, Antitumor; Enzyme Activation/drug effects; Humans

2'-,7'-dichlorofluorescin diacetate; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; Apoptosis; Brain tumor; Cancer therapy; DCFH-DA; DMEM; DMSO; Dulbecco's modified Eagle's medium; FBS; FCM; GBM; GSH; Glioma; JNK; MTT; N-acetyl-l-cysteine; NAC; Oxidative stress; PBS; PI; PL; Piplartine; ROS; c-jun N-terminal kinase; dimethyl sulfoxide; fetal bovine serum; flow cytometry; glioblastoma multiforme; glutathione; phosphate buffered saline; piperlongumine; propidium iodide; reactive oxygen species