Sodium accumulation is associated with disability and a progressive course in multiple sclerosis.

Paling, David; Solanky, Bhavana S; Riemer, Frank; Tozer, Daniel J; Wheeler-Kingshott, Claudia A M; Kapoor, Raju; Golay, Xavier; Miller, David H

Paling, David; Solanky, Bhavana S; Riemer, Frank; Tozer, Daniel J; Wheeler-Kingshott, Claudia A M; Kapoor, Raju; Golay, Xavier; Miller, David H.

Affiliation

Paling D; NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. d.paling@ucl.ac.uk

Brain ; 136(Pt 7): 2305-17, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23801742

Subject(s)

Disabled Persons; Disease Progression; Multiple Sclerosis/metabolism; Multiple Sclerosis/physiopathology; Sodium/metabolism; Adolescent; Adult; Aged; Analysis of Variance; Brain/metabolism; Brain/pathology; Disability Evaluation; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis/cerebrospinal fluid; Multiple Sclerosis/pathology; Sodium Isotopes; Statistics as Topic; Young Adult

Key words

MRI; Na+ channel; disability; disease progression; multiple sclerosis

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sodium / Disabled Persons / Disease Progression / Multiple Sclerosis Type of study: Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Brain Year: 2013 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google