Mer receptor tyrosine kinase is a therapeutic target in pre-B-cell acute lymphoblastic leukemia.

Linger, Rachel M A; Lee-Sherick, Alisa B; DeRyckere, Deborah; Cohen, Rebecca A; Jacobsen, Kristen M; McGranahan, Amy; Brandão, Luis N; Winges, Amanda; Sawczyn, Kelly K; Liang, Xiayuan; Keating, Amy K; Tan, Aik Choon; Earp, H Shelton; Graham, Douglas K

Linger, Rachel M A; Lee-Sherick, Alisa B; DeRyckere, Deborah; Cohen, Rebecca A; Jacobsen, Kristen M; McGranahan, Amy; Brandão, Luis N; Winges, Amanda; Sawczyn, Kelly K; Liang, Xiayuan; Keating, Amy K; Tan, Aik Choon; Earp, H Shelton; Graham, Douglas K.

Affiliation

Linger RM; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Blood ; 122(9): 1599-609, 2013 Aug 29.

Article in En | MEDLINE | ID: mdl-23861246

Subject(s)

Molecular Targeted Therapy; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Proto-Oncogene Proteins/antagonists & inhibitors; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors; Animals; Antineoplastic Agents/therapeutic use; Cell Line, Tumor; Gene Expression Regulation, Leukemic/drug effects; Gene Knockdown Techniques; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Small Interfering/pharmacology; RNA, Small Interfering/therapeutic use; Xenograft Model Antitumor Assays; c-Mer Tyrosine Kinase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Molecular Targeted Therapy Limits: Animals / Humans Language: En Journal: Blood Year: 2013 Type: Article Affiliation country: United States

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