Erythropoietin is involved in the angiogenic potential of bone marrow macrophages in multiple myeloma.

De Luisi, Annunziata; Binetti, Laura; Ria, Roberto; Ruggieri, Simona; Berardi, Simona; Catacchio, Ivana; Racanelli, Vito; Pavone, Vincenzo; Rossini, Bernardo; Vacca, Angelo; Ribatti, Domenico

De Luisi, Annunziata; Binetti, Laura; Ria, Roberto; Ruggieri, Simona; Berardi, Simona; Catacchio, Ivana; Racanelli, Vito; Pavone, Vincenzo; Rossini, Bernardo; Vacca, Angelo; Ribatti, Domenico.

Affiliation

De Luisi A; Department of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy.

Angiogenesis ; 16(4): 963-73, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23881169

Subject(s)

Bone Marrow/blood supply; Erythropoietin/pharmacology; Erythropoietin/physiology; Macrophages/physiology; Monoclonal Gammopathy of Undetermined Significance/physiopathology; Multiple Myeloma/physiopathology; Neoplasm Proteins/physiology; Neovascularization, Pathologic/physiopathology; Receptors, Erythropoietin/physiology; Aged; Androstadienes/pharmacology; Angiogenic Proteins/biosynthesis; Angiogenic Proteins/blood; Angiogenic Proteins/genetics; Angiogenic Proteins/metabolism; Animals; Bone Marrow Cells; Capillaries/ultrastructure; Cell Movement/drug effects; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane/blood supply; Chromones/pharmacology; Culture Media, Conditioned/pharmacology; Cytokines/blood; Epoetin Alfa; Humans; Macrophages/metabolism; Middle Aged; Morpholines/pharmacology; Multiple Myeloma/blood; Neoplasm Proteins/biosynthesis; Neoplasm Proteins/genetics; RNA Interference; RNA, Small Interfering/pharmacology; Receptors, Erythropoietin/antagonists & inhibitors; Receptors, Erythropoietin/biosynthesis; Receptors, Erythropoietin/genetics; Recombinant Proteins/pharmacology; Signal Transduction/drug effects; Signal Transduction/physiology; Up-Regulation/drug effects; Vascular Endothelial Growth Factor A/genetics; Vascular Endothelial Growth Factor A/pharmacology; Wortmannin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Monoclonal Gammopathy of Undetermined Significance / Erythropoietin / Receptors, Erythropoietin / Macrophages / Multiple Myeloma / Neoplasm Proteins / Neovascularization, Pathologic Language: En Journal: Angiogenesis Journal subject: HEMATOLOGIA Year: 2013 Type: Article Affiliation country: Italy

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