Mapping and kinetics of microglia/neuron cell-to-cell contacts in the 6-OHDA murine model of Parkinson's disease.

Virgone-Carlotta, Angélique; Uhlrich, Josselin; Akram, Muhammad Numan; Ressnikoff, Denis; Chrétien, Fabrice; Domenget, Chantal; Gherardi, Romain; Despars, Geneviève; Jurdic, Pierre; Honnorat, Jérôme; Nataf, Serge; Touret, Monique

Virgone-Carlotta, Angélique; Uhlrich, Josselin; Akram, Muhammad Numan; Ressnikoff, Denis; Chrétien, Fabrice; Domenget, Chantal; Gherardi, Romain; Despars, Geneviève; Jurdic, Pierre; Honnorat, Jérôme; Nataf, Serge; Touret, Monique.

Affiliation

Virgone-Carlotta A; INSERM U1028; CNRS UMR5292, Lyon Neurosciences Research Center, Neuro-oncology and Neuroinflammation team, Lyon 69000, France. angevi@hotmail.fr

Glia ; 61(10): 1645-58, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23893349

Subject(s)

Adrenergic Agents/toxicity; Cell Communication/physiology; Microglia/physiology; Neurons/physiology; Oxidopamine/toxicity; Parkinson Disease; Adaptor Proteins, Signal Transducing/genetics; Animals; Antigens, Differentiation/metabolism; Apomorphine; Cell Communication/drug effects; Cell Communication/genetics; Cell Count; Disease Models, Animal; Dopamine Agonists; Female; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Imaging, Three-Dimensional; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia/cytology; Microglia/drug effects; Microscopy, Confocal; Neurons/cytology; Neurons/drug effects; Parkinson Disease/etiology; Parkinson Disease/genetics; Parkinson Disease/pathology; Receptors, Interleukin-8A/deficiency; Rotation; Substantia Nigra/pathology; Time Factors; Tyrosine 3-Monooxygenase/metabolism

Key words

dopamine; neurodegeneration; neuroinflammation; substantia nigra

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Cell Communication / Oxidopamine / Microglia / Adrenergic Agents / Neurons Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Glia Journal subject: NEUROLOGIA Year: 2013 Type: Article Affiliation country: France

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