TGFß and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation.

Faherty, Noel; O'Donovan, Helen; Kavanagh, David; Madden, Stephen; McKay, Gareth J; Maxwell, Alexander P; Martin, Finian; Godson, Catherine; Crean, John

Faherty, Noel; O'Donovan, Helen; Kavanagh, David; Madden, Stephen; McKay, Gareth J; Maxwell, Alexander P; Martin, Finian; Godson, Catherine; Crean, John.

Affiliation

Faherty N; UCD School of Biomolecular and Biomedical Sciences, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

BMC Genomics ; 14: 525, 2013 Aug 01.

Article in En | MEDLINE | ID: mdl-23902294

Subject(s)

Actins/metabolism; Connective Tissue Growth Factor/pharmacology; Cyclic AMP Response Element-Binding Protein/metabolism; E2F1 Transcription Factor/metabolism; Gene Expression Regulation/drug effects; Transforming Growth Factor beta/pharmacology; Binding Sites; Cell Line; Cell Movement/drug effects; Cell Movement/genetics; Diabetic Nephropathies/genetics; Diabetic Nephropathies/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Humans; Hypertrophy/genetics; Mesangial Cells/drug effects; Mesangial Cells/metabolism; Protein Binding; Protein Interaction Maps; Reproducibility of Results; Signal Transduction/drug effects; Transcriptome; cdc42 GTP-Binding Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Transforming Growth Factor beta / Actins / Cyclic AMP Response Element-Binding Protein / E2F1 Transcription Factor / Connective Tissue Growth Factor Type of study: Prognostic_studies Limits: Humans Language: En Journal: BMC Genomics Journal subject: GENETICA Year: 2013 Type: Article Affiliation country: Ireland

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