Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.

Tober, Joanna; Yzaguirre, Amanda D; Piwarzyk, Eileen; Speck, Nancy A

Tober, Joanna; Yzaguirre, Amanda D; Piwarzyk, Eileen; Speck, Nancy A.

Affiliation

Tober J; Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Development ; 140(18): 3765-76, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23924635

Subject(s)

Core Binding Factor Alpha 2 Subunit/metabolism; Hematopoietic Stem Cells/metabolism; Animals; Aorta/cytology; Aorta/embryology; Cell Differentiation; Chickens; Colony-Forming Units Assay; Embryo, Mammalian/cytology; Embryo, Mammalian/metabolism; Endothelium/embryology; Endothelium/metabolism; Epigenesis, Genetic; Erythroid Precursor Cells/cytology; Erythroid Precursor Cells/metabolism; Fetus/embryology; Gene Deletion; Hematopoietic Stem Cells/cytology; Integrases/metabolism; Liver/cytology; Liver/embryology; Mice; Myeloid Progenitor Cells/cytology; Myeloid Progenitor Cells/metabolism; Time Factors; Yolk Sac/cytology

Key words

Embryo; Hematopoiesis; Hemogenic endothelium; Mouse; Runx1; Stem cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Core Binding Factor Alpha 2 Subunit Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2013 Type: Article Affiliation country: United States

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