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Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications.
Wei, Hui; Mo, Jingjie; Tao, Li; Russell, Reb J; Tymiak, Adrienne A; Chen, Guodong; Iacob, Roxana E; Engen, John R.
Affiliation
  • Wei H; Bioanalytical and Discovery Analytical Sciences, Research and Development, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Mo J; Bioanalytical and Discovery Analytical Sciences, Research and Development, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Tao L; Biologics Manufacturing and Process Development, Global Manufacturing and Supply, Bristol-Myers Squibb, Hopewell, NJ, USA.
  • Russell RJ; Biologics Manufacturing and Process Development, Global Manufacturing and Supply, Bristol-Myers Squibb, Bloomsbury, NJ, USA.
  • Tymiak AA; Bioanalytical and Discovery Analytical Sciences, Research and Development, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Chen G; Bioanalytical and Discovery Analytical Sciences, Research and Development, Bristol-Myers Squibb, Princeton, NJ, USA. Electronic address: Guodong.Chen@bms.com.
  • Iacob RE; Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA.
  • Engen JR; Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA. Electronic address: J.Engen@neu.edu.
Drug Discov Today ; 19(1): 95-102, 2014 Jan.
Article in En | MEDLINE | ID: mdl-23928097
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Deuterium / Protein Interaction Maps / Hydrogen Limits: Animals / Humans Language: En Journal: Drug Discov Today Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2014 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Deuterium / Protein Interaction Maps / Hydrogen Limits: Animals / Humans Language: En Journal: Drug Discov Today Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2014 Type: Article Affiliation country: United States