A placebo-controlled trial of acetyl-L-carnitine and &#945;-lipoic acid in the treatment of bipolar depression.

Brennan, Brian P; Jensen, John Eric; Hudson, James I; Coit, Caitlin E; Beaulieu, Ashley; Pope, Harrison G; Renshaw, Perry F; Cohen, Bruce M

A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression.

Brennan, Brian P; Jensen, John Eric; Hudson, James I; Coit, Caitlin E; Beaulieu, Ashley; Pope, Harrison G; Renshaw, Perry F; Cohen, Bruce M.

Affiliation

Brennan BP; Biological Psychiatry Laboratory, McLean Hospital, Belmont, MA 02478, USA. bbrennan@partners.org

J Clin Psychopharmacol ; 33(5): 627-35, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23948785

Subject(s)

Acetylcarnitine/therapeutic use; Antidepressive Agents/therapeutic use; Bipolar Disorder/drug therapy; Thioctic Acid/therapeutic use; Adult; Bipolar Disorder/diagnosis; Bipolar Disorder/metabolism; Bipolar Disorder/psychology; Brain/drug effects; Brain/metabolism; Chi-Square Distribution; Drug Therapy, Combination; Energy Metabolism/drug effects; Female; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria/drug effects; Mitochondria/metabolism; Phosphocreatine/metabolism; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetylcarnitine / Bipolar Disorder / Thioctic Acid / Antidepressive Agents Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Clin Psychopharmacol Year: 2013 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google