Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.

Lazear, Helen M; Pinto, Amelia K; Ramos, Hilario J; Vick, Sarah C; Shrestha, Bimmi; Suthar, Mehul S; Gale, Michael; Diamond, Michael S

Lazear, Helen M; Pinto, Amelia K; Ramos, Hilario J; Vick, Sarah C; Shrestha, Bimmi; Suthar, Mehul S; Gale, Michael; Diamond, Michael S.

Affiliation

Lazear HM; Departments of Medicine.

J Virol ; 87(21): 11401-15, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23966390

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Central Nervous System/immunology; DEAD-box RNA Helicases/immunology; Receptors, Pattern Recognition/immunology; West Nile Fever/immunology; West Nile virus/immunology; Animals; CD8-Positive T-Lymphocytes/virology; Central Nervous System/virology; DEAD-box RNA Helicases/deficiency; DEAD-box RNA Helicases/metabolism; Disease Models, Animal; Interferon-Induced Helicase, IFIH1; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Pattern Recognition/metabolism; Survival Analysis; Viral Load; West Nile Fever/virology; West Nile virus/isolation & purification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: West Nile Fever / West Nile virus / Central Nervous System / CD8-Positive T-Lymphocytes / Receptors, Pattern Recognition / DEAD-box RNA Helicases Limits: Animals Language: En Journal: J Virol Year: 2013 Type: Article

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