Synthesis of (±)-actinophyllic acid and analogs: applications of cascade reactions and diverted total synthesis.

Granger, Brett A; Jewett, Ivan T; Butler, Jeffrey D; Hua, Bruce; Knezevic, Claire E; Parkinson, Elizabeth I; Hergenrother, Paul J; Martin, Stephen F

Granger, Brett A; Jewett, Ivan T; Butler, Jeffrey D; Hua, Bruce; Knezevic, Claire E; Parkinson, Elizabeth I; Hergenrother, Paul J; Martin, Stephen F.

Affiliation

Granger BA; Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, United States.

J Am Chem Soc ; 135(35): 12984-6, 2013 Sep 04.

Article in En | MEDLINE | ID: mdl-23972114

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Indole Alkaloids/chemical synthesis; Indole Alkaloids/pharmacology; Antineoplastic Agents/chemistry; Cell Death/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indole Alkaloids/chemistry; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Indole Alkaloids / Antineoplastic Agents Limits: Humans Language: En Journal: J Am Chem Soc Year: 2013 Type: Article Affiliation country: United States

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