Slug expression inhibits calcitriol-mediated sensitivity to radiation in colorectal cancer.

Findlay, Victoria J; Moretz, R Eric; Wang, Cindy; Vaena, Silvia G; Bandurraga, Savannah G; Ashenafi, Michael; Marshall, David T; Watson, Dennis K; Camp, E Ramsay

Findlay, Victoria J; Moretz, R Eric; Wang, Cindy; Vaena, Silvia G; Bandurraga, Savannah G; Ashenafi, Michael; Marshall, David T; Watson, Dennis K; Camp, E Ramsay.

Affiliation

Findlay VJ; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina.

Mol Carcinog ; 53 Suppl 1: E130-9, 2014 Feb.

Article in En | MEDLINE | ID: mdl-23996472

Subject(s)

Calcitriol/pharmacology; Colorectal Neoplasms/pathology; Epithelial-Mesenchymal Transition/drug effects; Radiation-Sensitizing Agents/pharmacology; Transcription Factors/genetics; Blotting, Western; Cadherins/genetics; Cadherins/metabolism; Calcium Channel Agonists/pharmacology; Cell Adhesion/drug effects; Cell Adhesion/radiation effects; Cell Movement/drug effects; Cell Movement/radiation effects; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/metabolism; Colorectal Neoplasms/radiotherapy; Epithelial-Mesenchymal Transition/radiation effects; Fluorescent Antibody Technique; Gamma Rays; Humans; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Receptors, Calcitriol/genetics; Receptors, Calcitriol/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Transcription Factors/metabolism; Tumor Cells, Cultured; Vimentin/genetics; Vimentin/metabolism

Key words

EMT; Slug; cancer; colorectal; radiation; vitamin D

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Transcription Factors / Calcitriol / Colorectal Neoplasms / Epithelial-Mesenchymal Transition Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2014 Type: Article

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