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A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.
Shah, Sohela; Schrader, Kasmintan A; Waanders, Esmé; Timms, Andrew E; Vijai, Joseph; Miething, Cornelius; Wechsler, Jeremy; Yang, Jun; Hayes, James; Klein, Robert J; Zhang, Jinghui; Wei, Lei; Wu, Gang; Rusch, Michael; Nagahawatte, Panduka; Ma, Jing; Chen, Shann-Ching; Song, Guangchun; Cheng, Jinjun; Meyers, Paul; Bhojwani, Deepa; Jhanwar, Suresh; Maslak, Peter; Fleisher, Martin; Littman, Jason; Offit, Lily; Rau-Murthy, Rohini; Fleischut, Megan Harlan; Corines, Marina; Murali, Rajmohan; Gao, Xiaoni; Manschreck, Christopher; Kitzing, Thomas; Murty, Vundavalli V; Raimondi, Susana; Kuiper, Roland P; Simons, Annet; Schiffman, Joshua D; Onel, Kenan; Plon, Sharon E; Wheeler, David; Ritter, Deborah; Ziegler, David S; Tucker, Kathy; Sutton, Rosemary; Chenevix-Trench, Georgia; Li, Jun; Huntsman, David G; Hansford, Samantha; Senz, Janine.
Affiliation
  • Shah S; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Schrader KA; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Waanders E; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Timms AE; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Vijai J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Miething C; Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences and Radboud Institute for Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Wechsler J; Department of Pathology, University of Washington, Seattle, Washington, USA.
  • Yang J; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Hayes J; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Klein RJ; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Zhang J; Department of Pathology, University of Washington, Seattle, Washington, USA.
  • Wei L; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Wu G; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Rusch M; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Nagahawatte P; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Ma J; Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Chen SC; Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Song G; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Cheng J; Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Meyers P; Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Bhojwani D; Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Jhanwar S; Pediatric Cancer Genome Project Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Maslak P; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Fleisher M; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Littman J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Offit L; Pediatric Cancer Genome Project Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Rau-Murthy R; Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Fleischut MH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Corines M; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Murali R; Hematology Laboratory Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Gao X; Clinical Chemistry Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Manschreck C; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Kitzing T; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Murty VV; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Raimondi S; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Kuiper RP; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Simons A; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Schiffman JD; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Onel K; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Plon SE; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Wheeler D; Department of Pathology and Cell Biology, Columbia University, New York, New York, USA.
  • Ritter D; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Ziegler DS; Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences and Radboud Institute for Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Tucker K; Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences and Radboud Institute for Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Sutton R; High Risk Pediatric Cancer Clinic, Huntsman Cancer Institute/Primary Children's Medical Center, University of Utah, Salt Lake City, Utah, USA.
  • Chenevix-Trench G; Pediatrics, University of Chicago, Chicago, IL , USA.
  • Li J; Texas Children's Cancer Center and Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Huntsman DG; Texas Children's Cancer Center and Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Hansford S; Texas Children's Cancer Center and Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
  • Senz J; Kids Cancer Centre, Sydney Children's Hospital, Sydney, New South Wales, Australia, Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
Nat Genet ; 45(10): 1226-1231, 2013 Oct.
Article in En | MEDLINE | ID: mdl-24013638
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Germ-Line Mutation / Genetic Predisposition to Disease / PAX5 Transcription Factor Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2013 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Germ-Line Mutation / Genetic Predisposition to Disease / PAX5 Transcription Factor Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2013 Type: Article Affiliation country: United States