A neonatal amikacin covariate model can be used to predict ontogeny of other drugs eliminated through glomerular filtration in neonates.

De Cock, Roosmarijn F W; Allegaert, Karel; Sherwin, Catherine M T; Nielsen, Elisabet I; de Hoog, Matthijs; van den Anker, Johannes N; Danhof, Meindert; Knibbe, Catherijne A J

De Cock, Roosmarijn F W; Allegaert, Karel; Sherwin, Catherine M T; Nielsen, Elisabet I; de Hoog, Matthijs; van den Anker, Johannes N; Danhof, Meindert; Knibbe, Catherijne A J.

Affiliation

De Cock RF; Division of Pharmacology, LACDR, Leiden University, Leiden, The Netherlands.

Pharm Res ; 31(3): 754-67, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24065592

Subject(s)

Amikacin/metabolism; Anti-Bacterial Agents/metabolism; Kidney/physiology; Glomerular Filtration Rate; Humans; Infant, Newborn; Metabolic Clearance Rate; Models, Biological

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amikacin / Kidney / Anti-Bacterial Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans / Newborn Language: En Journal: Pharm Res Year: 2014 Type: Article Affiliation country: Netherlands

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