SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.

Kim, Eui Tae; White, Tommy E; Brandariz-Núñez, Alberto; Diaz-Griffero, Felipe; Weitzman, Matthew D

Kim, Eui Tae; White, Tommy E; Brandariz-Núñez, Alberto; Diaz-Griffero, Felipe; Weitzman, Matthew D.

Affiliation

Kim ET; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman Medical School and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

J Virol ; 87(23): 12949-56, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24067963

Subject(s)

DNA Replication; Herpes Simplex/metabolism; Herpes Simplex/virology; Herpesvirus 1, Human/genetics; Macrophages/virology; Monomeric GTP-Binding Proteins/metabolism; Cell Line; Down-Regulation; Herpes Simplex/genetics; Herpesvirus 1, Human/physiology; Host-Pathogen Interactions; Humans; Macrophages/metabolism; Monomeric GTP-Binding Proteins/genetics; SAM Domain and HD Domain-Containing Protein 1; Virus Replication

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Herpesvirus 1, Human / Monomeric GTP-Binding Proteins / DNA Replication / Herpes Simplex / Macrophages Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Virol Year: 2013 Type: Article Affiliation country: United States

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