No human virus sequences detected by next-generation sequencing in benign verrucous skin tumors occurring in BRAF-inhibitor-treated patients.

Ganzenmueller, Tina; Hage, Elias; Yakushko, Yuri; Kluba, Jeanette; Woltemate, Sabrina; Schacht, Vivien; Schulz, Thomas F; Gutzmer, Ralf

Ganzenmueller, Tina; Hage, Elias; Yakushko, Yuri; Kluba, Jeanette; Woltemate, Sabrina; Schacht, Vivien; Schulz, Thomas F; Gutzmer, Ralf.

Affiliation

Ganzenmueller T; Institute of Virology, Hannover Medical School, Hannover, Germany.

Exp Dermatol ; 22(11): 725-9, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24112647

Subject(s)

Carcinoma, Verrucous/virology; Melanoma/drug therapy; Proto-Oncogene Proteins B-raf/antagonists & inhibitors; Proto-Oncogene Proteins B-raf/metabolism; Skin Neoplasms/drug therapy; Skin Neoplasms/virology; Adult; Aged; Biopsy; Cell Proliferation; DNA, Viral/analysis; Female; Gene Library; High-Throughput Nucleotide Sequencing; Humans; Indoles/therapeutic use; Keratinocytes/cytology; Male; Middle Aged; Mutation; Papillomaviridae/genetics; Skin Neoplasms/complications; Sulfonamides/therapeutic use; Vemurafenib

Key words

BRAF inhibitors; cutaneous side effects; next-generation sequencing; verrucous keratosis; virus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Carcinoma, Verrucous / Proto-Oncogene Proteins B-raf / Melanoma Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Exp Dermatol Journal subject: DERMATOLOGIA Year: 2013 Type: Article Affiliation country: Germany

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