Reduced expression of &#945;GlcNAc in Barrett's oesophagus adjacent to Barrett's adenocarcinoma--a possible biomarker to predict the malignant potential of Barrett's oesophagus.

Iwaya, Yugo; Hasebe, Osamu; Koide, Naohiko; Kitahara, Kei; Suga, Tomoaki; Shinji, Akihiro; Muraki, Takashi; Yokosawa, Shuichi; Yamada, Shigenori; Arakura, Norikazu; Tanaka, Eiji; Nakayama, Jun

Reduced expression of αGlcNAc in Barrett's oesophagus adjacent to Barrett's adenocarcinoma--a possible biomarker to predict the malignant potential of Barrett's oesophagus.

Iwaya, Yugo; Hasebe, Osamu; Koide, Naohiko; Kitahara, Kei; Suga, Tomoaki; Shinji, Akihiro; Muraki, Takashi; Yokosawa, Shuichi; Yamada, Shigenori; Arakura, Norikazu; Tanaka, Eiji; Nakayama, Jun.

Affiliation

Iwaya Y; Department of Molecular Pathology, Shinshu University Graduate School of Medicine, Matsumoto, Japan; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.

Histopathology ; 64(4): 536-46, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24117499

Subject(s)

Acetylglucosamine/metabolism; Adenocarcinoma/metabolism; Adenocarcinoma/pathology; Barrett Esophagus/metabolism; Barrett Esophagus/pathology; Esophageal Neoplasms/metabolism; Esophageal Neoplasms/pathology; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor/metabolism; CDX2 Transcription Factor; Case-Control Studies; Disease Progression; Female; Homeodomain Proteins/metabolism; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Mucin-6/metabolism; Polysaccharides/metabolism

Key words

Barrett's adenocarcinoma; O-glycan; immunohistochemistry; mucin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetylglucosamine / Barrett Esophagus / Esophageal Neoplasms / Adenocarcinoma Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Histopathology Year: 2014 Type: Article Affiliation country: Japan

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