Circulating precursor CCR7(lo)PD-1(hi) CXCR5âº CD4âº T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di

Circulating precursor CCR7(lo)PD-1(hi) CXCR5âº CD4âº T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di.

Affiliation

He J; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.

Immunity ; 39(4): 770-81, 2013 Oct 17.

Article in En | MEDLINE | ID: mdl-24138884

Subject(s)

Antibodies/immunology; Immunologic Memory; Programmed Cell Death 1 Receptor/immunology; Receptors, CXCR5/immunology; Receptors, CXCR/immunology; T-Lymphocytes, Helper-Inducer/immunology; Animals; Antigens/immunology; B-Lymphocytes/immunology; B-Lymphocytes/pathology; B-Lymphocytes/virology; Cell Differentiation; DNA-Binding Proteins/genetics; DNA-Binding Proteins/immunology; Gene Expression; Germinal Center/immunology; Germinal Center/pathology; Germinal Center/virology; Humans; Immunity, Humoral; Immunophenotyping; Inducible T-Cell Co-Stimulator Protein/genetics; Inducible T-Cell Co-Stimulator Protein/immunology; Mice; Programmed Cell Death 1 Receptor/genetics; Proto-Oncogene Proteins c-bcl-6; Receptors, CXCR/genetics; Receptors, CXCR5/genetics; T-Lymphocytes, Helper-Inducer/pathology; T-Lymphocytes, Helper-Inducer/virology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Helper-Inducer / Receptors, CXCR / Receptors, CXCR5 / Programmed Cell Death 1 Receptor / Immunologic Memory / Antibodies Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: China

Fulltext

XML

PubMed Links

Search on Google