Recombinant human LCAT normalizes plasma lipoprotein profile in LCAT deficiency.

Simonelli, Sara; Tinti, Cristina; Salvini, Laura; Tinti, Laura; Ossoli, Alice; Vitali, Cecilia; Sousa, Vitor; Orsini, Gaetano; Nolli, Maria Luisa; Franceschini, Guido; Calabresi, Laura

Simonelli, Sara; Tinti, Cristina; Salvini, Laura; Tinti, Laura; Ossoli, Alice; Vitali, Cecilia; Sousa, Vitor; Orsini, Gaetano; Nolli, Maria Luisa; Franceschini, Guido; Calabresi, Laura.

Affiliation

Simonelli S; Centro E. Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.

Biologicals ; 41(6): 446-9, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24140107

Subject(s)

Lecithin Cholesterol Acyltransferase Deficiency/blood; Lipoproteins/blood; Phosphatidylcholine-Sterol O-Acyltransferase/blood; Recombinant Proteins/blood; Blotting, Western; Cholesterol/blood; Cholesterol/metabolism; Family Health; HEK293 Cells; Humans; Lecithin Cholesterol Acyltransferase Deficiency/genetics; Lipoproteins/metabolism; Mutation; Phosphatidylcholine-Sterol O-Acyltransferase/genetics; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism; Recombinant Proteins/metabolism

Key words

CE; FED; FLD; FPLC; Familial LCAT deficiency; HDL; LCAT; Lipoproteins; apoA-I; apolipoprotein A-I; cholesteryl esters; familial LCAT deficiency; fast performance liquid chromatography; fish-eye disease; lecithin:cholesterol acyltransferase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Phosphatidylcholine-Sterol O-Acyltransferase / Lecithin Cholesterol Acyltransferase Deficiency / Lipoproteins Limits: Humans Language: En Journal: Biologicals Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: Italy

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