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Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.
Tomecki, Rafal; Drazkowska, Karolina; Kucinski, Iwo; Stodus, Krystian; Szczesny, Roman J; Gruchota, Jakub; Owczarek, Ewelina P; Kalisiak, Katarzyna; Dziembowski, Andrzej.
Affiliation
  • Tomecki R; Department of Biophysics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland, Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland and International Institute of Molecular and Cell Biology, Trojdena 4, 02-109 Warsaw, Poland.
Nucleic Acids Res ; 42(2): 1270-90, 2014 Jan.
Article in En | MEDLINE | ID: mdl-24150935
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Exosome Multienzyme Ribonuclease Complex / Multiple Myeloma / Mutation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2014 Type: Article Affiliation country: Poland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Exosome Multienzyme Ribonuclease Complex / Multiple Myeloma / Mutation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2014 Type: Article Affiliation country: Poland