Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension.

Schmeisser, Sebastian; Priebe, Steffen; Groth, Marco; Monajembashi, Shamci; Hemmerich, Peter; Guthke, Reinhard; Platzer, Matthias; Ristow, Michael

Schmeisser, Sebastian; Priebe, Steffen; Groth, Marco; Monajembashi, Shamci; Hemmerich, Peter; Guthke, Reinhard; Platzer, Matthias; Ristow, Michael.

Affiliation

Schmeisser S; Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany ; Leibniz Graduate School of Aging, Leibniz Institute for Age Research, Fritz-Lipmann-Institute, Jena D-07745, Germany.

Mol Metab ; 2(2): 92-102, 2013.

Article in En | MEDLINE | ID: mdl-24199155

Key words

AAK, C. elegans AMP-activated protein kinase; Aging; BHA, butylated hydroxyl-anisole; Caenorhabditis elegans; DAF, abnormal dauer formation; Dietary restriction; EAT, eating: abnormal pharyngeal pumping; FoxO, forkhead box protein O; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Mitochondria; Mitohormesis; NRF, nuclear factor erythroid 2-related factor; PMK, C. elegans p38 map kinase family; Reactive oxygen species; Redox signaling; SIR, yeast silent information regulator related; SKN, skinhead

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Metab Year: 2013 Type: Article Affiliation country: Germany

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Metab Year: 2013 Type: Article Affiliation country: Germany