Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-&#945;-induced pulmonary fibrosis.

Madala, Satish K; Edukulla, Ramakrishna; Schmidt, Stephanie; Davidson, Cynthia; Ikegami, Machiko; Hardie, William D

Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.

Madala, Satish K; Edukulla, Ramakrishna; Schmidt, Stephanie; Davidson, Cynthia; Ikegami, Machiko; Hardie, William D.

Affiliation

Madala SK; 1 Department of Pediatrics, Divisions of Pulmonary Medicine and.

Am J Respir Cell Mol Biol ; 50(4): 777-86, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24199692

Subject(s)

Bone Marrow Cells/metabolism; Cell Movement; Cell Proliferation; Fibroblasts/metabolism; Lung/metabolism; Pulmonary Fibrosis/metabolism; Stromal Cells/metabolism; Transforming Growth Factor alpha/metabolism; Adoptive Transfer; Animals; Bone Marrow Cells/pathology; Bone Marrow Transplantation; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Disease Progression; Fibroblasts/pathology; Fibroblasts/transplantation; Genes, Reporter; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Hyaluronan Receptors/metabolism; Hydroxyproline/metabolism; Lung/pathology; Mice; Mice, Transgenic; Pulmonary Fibrosis/genetics; Pulmonary Fibrosis/pathology; Stromal Cells/pathology; Stromal Cells/transplantation; Time Factors; Transforming Growth Factor alpha/genetics; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis / Bone Marrow Cells / Cell Movement / Transforming Growth Factor alpha / Stromal Cells / Cell Proliferation / Fibroblasts / Lung Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2014 Type: Article

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