Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K(d) -specific CD8+ T cells.

Rahir, Gwendoline; Wathelet, Nathalie; Hanoteau, Aurélie; Henin, Coralie; Oldenhove, Guillaume; Galuppo, Adrien; Lanaya, Hanane; Colau, Didier; Mackay, Charles R; Van den Eynde, Benoit; Moser, Muriel

Rahir, Gwendoline; Wathelet, Nathalie; Hanoteau, Aurélie; Henin, Coralie; Oldenhove, Guillaume; Galuppo, Adrien; Lanaya, Hanane; Colau, Didier; Mackay, Charles R; Van den Eynde, Benoit; Moser, Muriel.

Affiliation

Rahir G; Department of Molecular Biology, Université Libre de Bruxelles, Gosselies, Belgium.

Int J Cancer ; 134(12): 2841-52, 2014 Jun 15.

Article in En | MEDLINE | ID: mdl-24249003

Subject(s)

Antineoplastic Agents, Alkylating/pharmacology; CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Cyclophosphamide/therapeutic use; Mastocytoma/drug therapy; Animals; Cell Line, Tumor; Cell Movement/immunology; Cell Proliferation; Dendritic Cells/immunology; H-2 Antigens/immunology; Integrin beta3/immunology; Lymph Nodes/cytology; Lymphocyte Activation/immunology; Mastocytoma/immunology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Receptors, CXCR3/metabolism

Key words

chemokines; cyclophosphamide; dendritic cells; infiltration; tumor antigens

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / CD8-Positive T-Lymphocytes / Antineoplastic Agents, Alkylating / Cyclophosphamide / Mastocytoma Limits: Animals Language: En Journal: Int J Cancer Year: 2014 Type: Article Affiliation country: Belgium

Fulltext

XML

PubMed Links

Search on Google