Localized interleukin-12 delivery for immunotherapy of solid tumours.

Wei, Louis Z; Xu, Yixin; Nelles, E Megan; Furlonger, Caren; Wang, James C M; Di Grappa, Marco A; Khokha, Rama; Medin, Jeffrey A; Paige, Christopher J

Wei, Louis Z; Xu, Yixin; Nelles, E Megan; Furlonger, Caren; Wang, James C M; Di Grappa, Marco A; Khokha, Rama; Medin, Jeffrey A; Paige, Christopher J.

Affiliation

Wei LZ; Department of Immunology, University of Toronto, Toronto, ON, Canada; Ontario Cancer Institute, University Health Network, Toronto, ON, Canada.

J Cell Mol Med ; 17(11): 1465-74, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24251770

Subject(s)

Carcinoma, Squamous Cell/therapy; Head and Neck Neoplasms/therapy; Immunotherapy; Interleukin-12/physiology; Animals; CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Cancer Vaccines/immunology; Carcinoma, Squamous Cell/immunology; Cell Line, Tumor; Female; Head and Neck Neoplasms/immunology; Immunologic Memory; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation

Key words

Interleukin-12; gene therapy; immunotherapy; lentivirus; solid tumour

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Interleukin-12 / Head and Neck Neoplasms / Immunotherapy Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2013 Type: Article Affiliation country: Canada

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