Anti-Bacterial Agents/pharmacology; Clostridioides difficile/drug effects; Clostridium Infections/drug therapy; Enterocolitis, Pseudomembranous/drug therapy; Oxazolidinones/pharmacology; Spores, Bacterial/drug effects; Acetamides/pharmacology; Animals; Bacterial Proteins/antagonists & inhibitors; Bacterial Proteins/biosynthesis; Bacterial Toxins/antagonists & inhibitors; Bacterial Toxins/biosynthesis; Clostridioides difficile/growth & development; Clostridioides difficile/metabolism; Clostridium Infections/microbiology; Clostridium Infections/mortality; Cricetinae; Enterocolitis, Pseudomembranous/microbiology; Enterocolitis, Pseudomembranous/mortality; Enterotoxins/antagonists & inhibitors; Enterotoxins/biosynthesis; Female; Fluoroquinolones/pharmacology; Humans; Linezolid; Male; Metronidazole/pharmacology; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Spores, Bacterial/growth & development; Survival Analysis; Vancomycin/pharmacology