Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons.

Liu, Wenjing; Devaux, Jérôme J

Liu, Wenjing; Devaux, Jérôme J.

Affiliation

Liu W; Aix Marseille Université, CNRS, CRN2M-UMR7286, 13344 Marseille Cedex 15, Marseille, France.
Devaux JJ; Aix Marseille Université, CNRS, CRN2M-UMR7286, 13344 Marseille Cedex 15, Marseille, France. Electronic address: jerome.devaux@univ-amu.fr.

Mol Cell Neurosci ; 58: 40-52, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24333508

Subject(s)

Calmodulin/metabolism; KCNQ2 Potassium Channel/metabolism; KCNQ3 Potassium Channel/metabolism; Nerve Tissue Proteins/metabolism; Neurons/metabolism; Protein Multimerization; Amino Acid Sequence; Animals; Cells, Cultured; KCNQ2 Potassium Channel/chemistry; KCNQ2 Potassium Channel/genetics; KCNQ3 Potassium Channel/chemistry; KCNQ3 Potassium Channel/genetics; Male; Molecular Sequence Data; Mutation; Nerve Tissue Proteins/chemistry; Nerve Tissue Proteins/genetics; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Rats, Wistar

Key words

1510; Calcium; Epilepsy; Excitability; IQ domain; Node of Ranvier; Voltage-gated potassium channel

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calmodulin / KCNQ2 Potassium Channel / KCNQ3 Potassium Channel / Protein Multimerization / Nerve Tissue Proteins / Neurons Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2014 Type: Article Affiliation country: France

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