Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy.

Díaz Flaqué, María C; Galigniana, Natalia M; Béguelin, Wendy; Vicario, Rocío; Proietti, Cecilia J; Russo, Rosalía; Rivas, Martín A; Tkach, Mercedes; Guzmán, Pablo; Roa, Juan C; Maronna, Esteban; Pineda, Viviana; Muñoz, Sergio; Mercogliano, María; Charreau, Eduardo H; Yankilevich, Patricio; Schillaci, Roxana; Elizalde, Patricia V

Díaz Flaqué, María C; Galigniana, Natalia M; Béguelin, Wendy; Vicario, Rocío; Proietti, Cecilia J; Russo, Rosalía; Rivas, Martín A; Tkach, Mercedes; Guzmán, Pablo; Roa, Juan C; Maronna, Esteban; Pineda, Viviana; Muñoz, Sergio; Mercogliano, María; Charreau, Eduardo H; Yankilevich, Patricio; Schillaci, Roxana; Elizalde, Patricia V.

Breast Cancer Res ; 15(6): R118, 2013 Dec 17.

Article in En | MEDLINE | ID: mdl-24345432

Subject(s)

Breast Neoplasms/drug therapy; Breast Neoplasms/metabolism; Receptor, ErbB-2/metabolism; Receptors, Progesterone/metabolism; STAT3 Transcription Factor/metabolism; Transcription Factor AP-1/metabolism; Animals; Breast Neoplasms/mortality; Breast Neoplasms/pathology; Cell Nucleus/drug effects; Cyclin D1/genetics; Cyclin D1/metabolism; Female; Follow-Up Studies; Humans; Medroxyprogesterone Acetate/pharmacology; Mice, Inbred BALB C; Phosphorylation/drug effects; Promoter Regions, Genetic; Receptor, ErbB-2/genetics; Retrospective Studies; Selective Estrogen Receptor Modulators/therapeutic use; Tamoxifen/therapeutic use; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Progesterone / Transcription Factor AP-1 / Receptor, ErbB-2 / STAT3 Transcription Factor Type of study: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2013 Type: Article

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