A tryptophan metabolite, kynurenine, promotes mast cell activation through aryl hydrocarbon receptor.

Kawasaki, H; Chang, H-W; Tseng, H-C; Hsu, S-C; Yang, S-J; Hung, C-H; Zhou, Y; Huang, S-K

Kawasaki, H; Chang, H-W; Tseng, H-C; Hsu, S-C; Yang, S-J; Hung, C-H; Zhou, Y; Huang, S-K.

Affiliation

Kawasaki H; National Health Research Institutes, Zhu-Nan, Taiwan.

Allergy ; 69(4): 445-52, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24397465

Subject(s)

Kynurenine/pharmacology; Mast Cells/immunology; Mast Cells/metabolism; Receptors, Aryl Hydrocarbon/metabolism; Tryptophan/metabolism; Animals; Bone Marrow Cells/drug effects; Bone Marrow Cells/immunology; Bone Marrow Cells/metabolism; Cells, Cultured; Humans; Immunoglobulin E/immunology; Kynurenine/administration & dosage; Mast Cells/drug effects; Mice; Signal Transduction/drug effects

Key words

aryl hydrocarbon receptor; kynurenine; mast cell; tryptophan metabolite

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tryptophan / Receptors, Aryl Hydrocarbon / Kynurenine / Mast Cells Limits: Animals / Humans Language: En Journal: Allergy Year: 2014 Type: Article Affiliation country: Taiwan

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