Molecular and genetic diversity in the metastatic process of melanoma.

Harbst, Katja; Lauss, Martin; Cirenajwis, Helena; Winter, Christof; Howlin, Jillian; Törngren, Therese; Kvist, Anders; Nodin, Björn; Olsson, Eleonor; Häkkinen, Jari; Jirström, Karin; Staaf, Johan; Lundgren, Lotta; Olsson, Håkan; Ingvar, Christian; Gruvberger-Saal, Sofia K; Saal, Lao H; Jönsson, Göran

Harbst, Katja; Lauss, Martin; Cirenajwis, Helena; Winter, Christof; Howlin, Jillian; Törngren, Therese; Kvist, Anders; Nodin, Björn; Olsson, Eleonor; Häkkinen, Jari; Jirström, Karin; Staaf, Johan; Lundgren, Lotta; Olsson, Håkan; Ingvar, Christian; Gruvberger-Saal, Sofia K; Saal, Lao H; Jönsson, Göran.

Affiliation

Harbst K; Department of Oncology, Clinical Sciences, Lund University, Sweden; CREATE Health Strategic Centre for Clinical Cancer Research, Lund University, Sweden.

J Pathol ; 233(1): 39-50, 2014 May.

Article in En | MEDLINE | ID: mdl-24399611

Subject(s)

Biomarkers, Tumor/genetics; Melanoma/genetics; Melanoma/secondary; Mutation; Skin Neoplasms/genetics; Skin Neoplasms/pathology; Adult; Aged; Aged, 80 and over; Antigens, CD; Cadherins/genetics; Chromosomes, Human; DNA Copy Number Variations; DNA Mutational Analysis/methods; Disease Progression; Female; GTP Phosphohydrolases/genetics; Gene Dosage; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Lymphatic Metastasis; Male; Membrane Proteins/genetics; Middle Aged; PTEN Phosphohydrolase/genetics; Phenotype; Proto-Oncogene Proteins B-raf/genetics; Transcriptome

Key words

BRAF; NRAS; deep sequencing; gene expression; melanoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Biomarkers, Tumor / Melanoma / Mutation Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Pathol Year: 2014 Type: Article Affiliation country: Sweden

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