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Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication.
Munagala, Surendrachary; Sirasani, Gopal; Kokkonda, Praveen; Phadke, Manali; Krynetskaia, Natalia; Lu, Peihua; Sharom, Frances J; Chaudhury, Sidhartha; Abdulhameed, Mohamed Diwan M; Tawa, Gregory; Wallqvist, Anders; Martinez, Rogelio; Childers, Wayne; Abou-Gharbia, Magid; Krynetskiy, Evgeny; Andrade, Rodrigo B.
Affiliation
  • Munagala S; Department of Chemistry, Temple University, Philadelphia, PA 19122, United States.
  • Sirasani G; Department of Chemistry, Temple University, Philadelphia, PA 19122, United States.
  • Kokkonda P; Department of Chemistry, Temple University, Philadelphia, PA 19122, United States.
  • Phadke M; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Krynetskaia N; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Lu P; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
  • Sharom FJ; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
  • Chaudhury S; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702, United States.
  • Abdulhameed MD; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702, United States.
  • Tawa G; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702, United States.
  • Wallqvist A; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702, United States.
  • Martinez R; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Childers W; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Abou-Gharbia M; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Krynetskiy E; Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19122, United States.
  • Andrade RB; Department of Chemistry, Temple University, Philadelphia, PA 19122, United States. Electronic address: randrade@temple.edu.
Bioorg Med Chem ; 22(3): 1148-55, 2014 Feb 01.
Article in En | MEDLINE | ID: mdl-24405813
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Neoplasm / Strychnos / Alkaloids / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Neoplasm / Strychnos / Alkaloids / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: United States