Clinical significance of the ubiquitin ligase UBE3C in hepatocellular carcinoma revealed by exome sequencing.

Jiang, Jia-Hao; Liu, Yan-Feng; Ke, Ai-Wu; Gu, Fang-Ming; Yu, Yao; Dai, Zhi; Gao, Qiang; Shi, Guo-Ming; Liao, Bo-Yi; Xie, You-Hua; Fan, Jia; Huang, Xiao-Wu; Zhou, Jian

Jiang, Jia-Hao; Liu, Yan-Feng; Ke, Ai-Wu; Gu, Fang-Ming; Yu, Yao; Dai, Zhi; Gao, Qiang; Shi, Guo-Ming; Liao, Bo-Yi; Xie, You-Hua; Fan, Jia; Huang, Xiao-Wu; Zhou, Jian.

Affiliation

Jiang JH; Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, P.R. China.

Hepatology ; 59(6): 2216-27, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24425307

Subject(s)

Carcinoma, Hepatocellular/etiology; Exome/genetics; Hepatitis B, Chronic/complications; Liver Neoplasms/etiology; Ubiquitin-Protein Ligases/genetics; Amino Acid Substitution/genetics; Carcinogenesis/genetics; Carcinoma, Hepatocellular/enzymology; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Disease Progression; Female; Hepatitis B, Chronic/enzymology; Hepatitis B, Chronic/pathology; Humans; Liver Neoplasms/enzymology; Liver Neoplasms/pathology; Male; Middle Aged; Molecular Sequence Data; Mutation/genetics; Oligonucleotide Array Sequence Analysis; Oncogenes/genetics; Prognosis; Sequence Analysis, DNA; Ubiquitin-Protein Ligases/chemistry; Ubiquitin-Protein Ligases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Hepatitis B, Chronic / Ubiquitin-Protein Ligases / Exome / Liver Neoplasms Type of study: Prognostic_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2014 Type: Article

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