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Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes.
Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Sulem, Patrick; Helgason, Hannes; Grarup, Niels; Sigurdsson, Asgeir; Helgadottir, Hafdis T; Johannsdottir, Hrefna; Magnusson, Olafur T; Gudjonsson, Sigurjon A; Justesen, Johanne M; Harder, Marie N; Jørgensen, Marit E; Christensen, Cramer; Brandslund, Ivan; Sandbæk, Annelli; Lauritzen, Torsten; Vestergaard, Henrik; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Daneshpour, Maryam S; Fallah, Mohammad-Sadegh; Hreidarsson, Astradur B; Sigurdsson, Gunnar; Azizi, Fereidoun; Benediktsson, Rafn; Masson, Gisli; Helgason, Agnar; Kong, Augustine; Gudbjartsson, Daniel F; Pedersen, Oluf; Thorsteinsdottir, Unnur; Stefansson, Kari.
Affiliation
  • Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Sulem P; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Helgason H; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sigurdsson A; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Helgadottir HT; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Johannsdottir H; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Magnusson OT; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Gudjonsson SA; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Justesen JM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Harder MN; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark.
  • Christensen C; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark.
  • Brandslund I; 1] Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark. [2] Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
  • Sandbæk A; Department of Public Health, Section of General Practice, University of Aarhus, Aarhus, Denmark.
  • Lauritzen T; Department of Public Health, Section of General Practice, University of Aarhus, Aarhus, Denmark.
  • Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Linneberg A; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.
  • Jørgensen T; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. [2] Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [3] Faculty of Medicine, University of Aalborg, Aalborg, Denmark.
  • Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Daneshpour MS; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Fallah MS; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hreidarsson AB; Department of Endocrinology and Metabolism, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland.
  • Sigurdsson G; Department of Endocrinology and Metabolism, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland.
  • Azizi F; Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Benediktsson R; Department of Endocrinology and Metabolism, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland.
  • Masson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Helgason A; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Department of Anthropology, University of Iceland, Reykjavik, Iceland.
  • Kong A; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Gudbjartsson DF; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Thorsteinsdottir U; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Stefansson K; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Nat Genet ; 46(3): 294-8, 2014 Mar.
Article in En | MEDLINE | ID: mdl-24464100
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Trans-Activators / Homeodomain Proteins / Amidine-Lyases / Diabetes Mellitus, Type 2 / Cyclin D2 / Mixed Function Oxygenases Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: Asia / Europa Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Iceland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Trans-Activators / Homeodomain Proteins / Amidine-Lyases / Diabetes Mellitus, Type 2 / Cyclin D2 / Mixed Function Oxygenases Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: Asia / Europa Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Iceland