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Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.
Ndlovu, Hlumani; Darby, Mathew; Froelich, Monika; Horsnell, William; Lühder, Fred; Hünig, Thomas; Brombacher, Frank.
Affiliation
  • Ndlovu H; International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component and Institute of Infectious Diseases and Molecular Medicine (IIDMM), Division of Immunology, University of Cape Town, Cape Town, South Africa.
  • Darby M; International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component and Institute of Infectious Diseases and Molecular Medicine (IIDMM), Division of Immunology, University of Cape Town, Cape Town, South Africa.
  • Froelich M; Institute for Virology and Immunology, University of Würzburg, Würzburg, Germany.
  • Horsnell W; International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component and Institute of Infectious Diseases and Molecular Medicine (IIDMM), Division of Immunology, University of Cape Town, Cape Town, South Africa.
  • Lühder F; Department of Neuroimmunology, Institute of Multiple Sclerosis Research and The Hertie Foundation, University Medical Center Göttingen, Göttingen, Germany.
  • Hünig T; Institute for Virology and Immunology, University of Würzburg, Würzburg, Germany.
  • Brombacher F; International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component and Institute of Infectious Diseases and Molecular Medicine (IIDMM), Division of Immunology, University of Cape Town, Cape Town, South Africa.
PLoS Pathog ; 10(2): e1003906, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24516382
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Strongylida Infections / CD28 Antigens / Nippostrongylus Limits: Animals Country/Region as subject: America do sul / Brasil Language: En Journal: PLoS Pathog Year: 2014 Type: Article Affiliation country: South Africa
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Strongylida Infections / CD28 Antigens / Nippostrongylus Limits: Animals Country/Region as subject: America do sul / Brasil Language: En Journal: PLoS Pathog Year: 2014 Type: Article Affiliation country: South Africa