The molecular and metabolic influence of long term agmatine consumption.

Nissim, Itzhak; Horyn, Oksana; Daikhin, Yevgeny; Chen, Pan; Li, Changhong; Wehrli, Suzanne L; Nissim, Ilana; Yudkoff, Marc

Nissim, Itzhak; Horyn, Oksana; Daikhin, Yevgeny; Chen, Pan; Li, Changhong; Wehrli, Suzanne L; Nissim, Ilana; Yudkoff, Marc.

Affiliation

Nissim I; From the Children's Hospital of Philadelphia.

J Biol Chem ; 289(14): 9710-29, 2014 Apr 04.

Article in En | MEDLINE | ID: mdl-24523404

Subject(s)

Agmatine/pharmacology; Cyclic AMP/metabolism; Fatty Acids/metabolism; Gluconeogenesis/drug effects; Liver/metabolism; Obesity/drug therapy; Agmatine/pharmacokinetics; Animals; Biological Transport, Active/drug effects; Carnitine/analogs & derivatives; Carnitine/metabolism; Dietary Fats/adverse effects; Dietary Fats/pharmacology; Gene Expression Regulation/drug effects; Humans; Male; Metabolome; Obesity/chemically induced; Obesity/metabolism; Oxidation-Reduction/drug effects; PPAR gamma/biosynthesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factors/biosynthesis

Key words

Adenylate Cyclase (Adenylyl Cyclase); Carbohydrate Metabolism; Carnitine; Cyclic AMP (cAMP); Fatty Acid Oxidation; Insulin Resistance; Liver; Metabolic Syndrome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic AMP / Agmatine / Fatty Acids / Gluconeogenesis / Liver / Obesity Limits: Animals / Humans / Male Language: En Journal: J Biol Chem Year: 2014 Type: Article

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