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An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS.
Savage, Abigail L; Wilm, Thomas P; Khursheed, Kejhal; Shatunov, Aleksey; Morrison, Karen E; Shaw, Pamela J; Shaw, Christopher E; Smith, Bradley; Breen, Gerome; Al-Chalabi, Ammar; Moss, Diana; Bubb, Vivien J; Quinn, John P.
Affiliation
  • Savage AL; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool, United Kingdom.
  • Wilm TP; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool, United Kingdom.
  • Shatunov A; Clinical Neuroscience, Institute of Psychiatry, King's College London, London, United Kingdom.
  • Morrison KE; School of Clinical and Experimental Medicine, College of Medicine and Dentistry, University of Birmingham, Birmingham, United Kingdom; and Neurosciences Division, University Hospital Birmingham NHS Foundation Trust, Birmingham, West Midlands, United Kingdom.
  • Shaw PJ; Academic Unit of Neurology, Department of Neuroscience, Sheffield Institute for Translational Research, University of Sheffield, Sheffield, South Yorkshire, United Kingdom.
  • Shaw CE; Clinical Neuroscience, Institute of Psychiatry, King's College London, London, United Kingdom.
  • Smith B; Clinical Neuroscience, Institute of Psychiatry, King's College London, London, United Kingdom.
  • Breen G; MRC Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research, Centre for Mental Health, South London, United Kingdom; and Maudsley NHS Foundation Trust and Institute
  • Al-Chalabi A; Clinical Neuroscience, Institute of Psychiatry, King's College London, London, United Kingdom.
  • Moss D; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, The University of Liverpool, Liverpool, United Kingdom.
  • Bubb VJ; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool, United Kingdom.
  • Quinn JP; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool, United Kingdom.
PLoS One ; 9(6): e90833, 2014.
Article in En | MEDLINE | ID: mdl-24608899
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Promoter Regions, Genetic / RNA-Binding Protein FUS / Amyotrophic Lateral Sclerosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Promoter Regions, Genetic / RNA-Binding Protein FUS / Amyotrophic Lateral Sclerosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Type: Article Affiliation country: United kingdom