Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.

Labi, Verena; Woess, Claudia; Tuzlak, Selma; Erlacher, Miriam; Bouillet, Philippe; Strasser, Andreas; Tzankov, Alexandar; Villunger, Andreas

Labi, Verena; Woess, Claudia; Tuzlak, Selma; Erlacher, Miriam; Bouillet, Philippe; Strasser, Andreas; Tzankov, Alexandar; Villunger, Andreas.

Affiliation

Labi V; Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria;

Blood ; 123(17): 2652-62, 2014 Apr 24.

Article in En | MEDLINE | ID: mdl-24632712

Subject(s)

Adaptor Proteins, Signal Transducing/genetics; Apoptosis Regulatory Proteins/genetics; Cell Death; Homeostasis; Lymphocytes/cytology; Membrane Proteins/genetics; Proto-Oncogene Proteins/genetics; Adaptor Proteins, Signal Transducing/physiology; Animals; Apoptosis; Apoptosis Regulatory Proteins/physiology; Autoantibodies/immunology; Autoimmunity; Bcl-2-Like Protein 11; Cell Separation; Female; Flow Cytometry; Genotype; Immune System; Immunoglobulins/immunology; Male; Membrane Proteins/physiology; Mice; Mice, Transgenic; Phenotype; Protein Structure, Tertiary; Proto-Oncogene Proteins/physiology; Thymocytes/cytology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes / Proto-Oncogene Proteins / Cell Death / Adaptor Proteins, Signal Transducing / Apoptosis Regulatory Proteins / Homeostasis / Membrane Proteins Limits: Animals Language: En Journal: Blood Year: 2014 Type: Article

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