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The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2.
Winters, Michael P; Teleha, Christopher A; Kang, Fu-An; McComsey, David; O'Neill, John C; Hou, Cuifen; Kirchner, Thomas; Wang, Ping; Johnson, Dana; Sui, Zhihua.
Affiliation
  • Winters MP; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA. Electronic address: mwinter4@its.jnj.com.
  • Teleha CA; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Kang FA; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • McComsey D; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • O'Neill JC; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Hou C; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Kirchner T; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Wang P; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Johnson D; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
  • Sui Z; Janssen Research and Development, LLC, 1400 McKean Rd., Spring House, PA 19477, USA.
Bioorg Med Chem Lett ; 24(9): 2137-40, 2014 May 01.
Article in En | MEDLINE | ID: mdl-24685539

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CCR2 / Furans Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CCR2 / Furans Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article