microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells.

Tezcan, Gulcin; Tunca, Berrin; Bekar, Ahmet; Preusser, Matthias; Berghoff, Anna Sophie; Egeli, Unal; Cecener, Gulsah; Ricken, Gerda; Budak, Ferah; Taskapilioglu, Mevlut Ozgur; Kocaeli, Hasan; Tolunay, Sahsine

Tezcan, Gulcin; Tunca, Berrin; Bekar, Ahmet; Preusser, Matthias; Berghoff, Anna Sophie; Egeli, Unal; Cecener, Gulsah; Ricken, Gerda; Budak, Ferah; Taskapilioglu, Mevlut Ozgur; Kocaeli, Hasan; Tolunay, Sahsine.

Affiliation

Tezcan G; Department of Medical Biology, Medical Faculty, Uludag University, Bursa, Turkey.

Cell Mol Neurobiol ; 34(5): 679-92, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24691539

Subject(s)

Brain Neoplasms/metabolism; Dacarbazine/analogs & derivatives; Gene Expression Regulation, Neoplastic; Glioblastoma/metabolism; MicroRNAs/biosynthesis; Neoplastic Stem Cells/metabolism; Aged; Antineoplastic Agents, Alkylating/pharmacology; Antineoplastic Agents, Alkylating/therapeutic use; Brain Neoplasms/drug therapy; Brain Neoplasms/mortality; Cohort Studies; Dacarbazine/pharmacology; Dacarbazine/therapeutic use; Drug Resistance, Neoplasm/drug effects; Drug Resistance, Neoplasm/physiology; Female; Glioblastoma/drug therapy; Glioblastoma/mortality; Humans; Male; Middle Aged; Neoplastic Stem Cells/drug effects; Survival Rate/trends; Temozolomide; Treatment Outcome; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Gene Expression Regulation, Neoplastic / Glioblastoma / Dacarbazine / MicroRNAs Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Cell Mol Neurobiol Year: 2014 Type: Article Affiliation country: Turkey

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