Altered nucleosome positioning at the transcription start site and deficient transcriptional initiation in Friedreich ataxia.

Chutake, Yogesh K; Costello, Whitney N; Lam, Christina; Bidichandani, Sanjay I

Chutake, Yogesh K; Costello, Whitney N; Lam, Christina; Bidichandani, Sanjay I.

Affiliation

Chutake YK; From the Departments of Pediatrics and.
Costello WN; From the Departments of Pediatrics and.
Lam C; From the Departments of Pediatrics and.
Bidichandani SI; From the Departments of Pediatrics and Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104 Sanjay-Bidichandani@ouhsc.edu.

J Biol Chem ; 289(22): 15194-202, 2014 May 30.

Article in En | MEDLINE | ID: mdl-24737321

Subject(s)

Friedreich Ataxia/genetics; Iron-Binding Proteins/genetics; Nucleosomes/genetics; Transcription Elongation, Genetic/physiology; Transcription Initiation Site/physiology; Cell Line; Chromatin Assembly and Disassembly/physiology; Gene Expression Profiling; Heterochromatin/physiology; Humans; Introns/genetics; Promoter Regions, Genetic/genetics; Transcription, Genetic/genetics; Trinucleotide Repeats/genetics; Frataxin

Key words

Expanded Triplet Repeat; Friedreich Ataxia; Gene Transcription; Heterochromatin; Neurological Diseases; Nucleosome Positioning; Nucleotide Repeat Disease; Transcription Promoter; Transcription Start Site

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Friedreich Ataxia / Nucleosomes / Transcription Initiation Site / Iron-Binding Proteins / Transcription Elongation, Genetic Limits: Humans Language: En Journal: J Biol Chem Year: 2014 Type: Article

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