Early detection of thrombin activity in neuroinflammatory disease.

Davalos, Dimitrios; Baeten, Kim M; Whitney, Michael A; Mullins, Eric S; Friedman, Beth; Olson, Emilia S; Ryu, Jae Kyu; Smirnoff, Dimitri S; Petersen, Mark A; Bedard, Catherine; Degen, Jay L; Tsien, Roger Y; Akassoglou, Katerina

Davalos, Dimitrios; Baeten, Kim M; Whitney, Michael A; Mullins, Eric S; Friedman, Beth; Olson, Emilia S; Ryu, Jae Kyu; Smirnoff, Dimitri S; Petersen, Mark A; Bedard, Catherine; Degen, Jay L; Tsien, Roger Y; Akassoglou, Katerina.

Affiliation

Davalos D; Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA.

Ann Neurol ; 75(2): 303-8, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24740641

Subject(s)

Encephalomyelitis, Autoimmune, Experimental/metabolism; Encephalomyelitis, Autoimmune, Experimental/pathology; Thrombin/metabolism; Animals; Axons/pathology; Blood Coagulation Factors/chemistry; Connexin 30; Connexins/genetics; Demyelinating Diseases/etiology; Demyelinating Diseases/pathology; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental/chemically induced; Fibrin/metabolism; Green Fluorescent Proteins/genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Basic Protein/metabolism; Myelin-Oligodendrocyte Glycoprotein/toxicity; Peptide Fragments/toxicity; Poly I-C/toxicity; Thrombin/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombin / Encephalomyelitis, Autoimmune, Experimental Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Ann Neurol Year: 2014 Type: Article Affiliation country: Canada

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