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A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis.
Ramos, Yolande F M; Bos, Steffan D; van der Breggen, Ruud; Kloppenburg, Margreet; Ye, Kai; Lameijer, Eric-Wubbo E M W; Nelissen, Rob G H H; Slagboom, P Eline; Meulenbelt, Ingrid.
Affiliation
  • Ramos YF; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.
  • Bos SD; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.
  • van der Breggen R; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Kloppenburg M; Department of Rheumatology & Department of Clinical Epidemiology, Leiden, The Netherlands.
  • Ye K; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Lameijer EW; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Nelissen RG; Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
  • Slagboom PE; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.
  • Meulenbelt I; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.
Ann Rheum Dis ; 74(9): 1756-62, 2015 Sep.
Article in En | MEDLINE | ID: mdl-24743232
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Chondrocalcinosis / Osteoprotegerin Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Rheum Dis Year: 2015 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Chondrocalcinosis / Osteoprotegerin Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Rheum Dis Year: 2015 Type: Article Affiliation country: Netherlands