Genetic variants may play an important role in mRNA-miRNA interaction: evidence for haplotype-dependent downregulation of ABCC2 (MRP2) by miRNA-379.

Werk, Anneke N; Bruckmueller, Henrike; Haenisch, Sierk; Cascorbi, Ingolf

Werk, Anneke N; Bruckmueller, Henrike; Haenisch, Sierk; Cascorbi, Ingolf.

Affiliation

Werk AN; Institute for Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel, Germany.

Pharmacogenet Genomics ; 24(6): 283-91, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24743544

Subject(s)

MicroRNAs/genetics; Multidrug Resistance-Associated Proteins/biosynthesis; RNA, Messenger/genetics; Adult; Female; Gene Expression Regulation; Haplotypes; Humans; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins/genetics; Polymorphism, Single Nucleotide; RNA Stability/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Multidrug Resistance-Associated Proteins / MicroRNAs Limits: Adult / Female / Humans Language: En Journal: Pharmacogenet Genomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Germany

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