Vitamin D deficiency promotes epithelial barrier dysfunction and intestinal inflammation.

Assa, Amit; Vong, Linda; Pinnell, Lee J; Avitzur, Naama; Johnson-Henry, Kathene C; Sherman, Philip M

Assa, Amit; Vong, Linda; Pinnell, Lee J; Avitzur, Naama; Johnson-Henry, Kathene C; Sherman, Philip M.

Affiliation

Assa A; Cell Biology Program, Research Institute Department of Paediatrics, Hospital for Sick Children.
Vong L; Cell Biology Program, Research Institute.
Pinnell LJ; Cell Biology Program, Research Institute.
Avitzur N; Cell Biology Program, Research Institute.
Johnson-Henry KC; Cell Biology Program, Research Institute.
Sherman PM; Cell Biology Program, Research Institute Department of Paediatrics, Hospital for Sick Children University of Toronto, Canada.

J Infect Dis ; 210(8): 1296-305, 2014 Oct 15.

Article in En | MEDLINE | ID: mdl-24755435

Subject(s)

Calcitriol/pharmacology; Inflammation/metabolism; Intestinal Diseases/metabolism; Intestinal Mucosa/physiopathology; Vitamin D Deficiency/pathology; Animals; Caco-2 Cells; Citrobacter rodentium; Colitis/etiology; Enterobacteriaceae Infections/microbiology; Enterohemorrhagic Escherichia coli; Escherichia coli Infections; Feces/microbiology; Humans; Intestinal Mucosa/pathology; Mice; Mice, Inbred C57BL; Vitamin D Deficiency/metabolism

Key words

barrier function; colitis; dysbiosis; microbiome; vitamin D

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin D Deficiency / Calcitriol / Inflammation / Intestinal Diseases / Intestinal Mucosa Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: J Infect Dis Year: 2014 Type: Article

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