Matrix effect in ligand-binding assay: the importance of evaluating emerging technologies.

Crisino, Rebecca M; Luo, Linlin; Geist, Brian; Zoghbi, Jad; Spriggs, Franklin

Crisino, Rebecca M; Luo, Linlin; Geist, Brian; Zoghbi, Jad; Spriggs, Franklin.

Affiliation

Crisino RM; Janssen R&D, L.L.C., 200 Great Valley Parkway, Malvern, PA, USA. rcrisino@its.jnj.com.

Bioanalysis ; 6(8): 1033-6, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24830885

Subject(s)

Immunoassay/methods; Antibodies/analysis; Humans; Immunoassay/instrumentation; Immunoassay/standards; Inventions; Pharmaceutical Preparations/analysis

Key words

emerging technology; immunogenicity; innovation; ligand-binding assay; matrix effect; matrix interference; pharmacokinetic; technology evaluation

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoassay Limits: Humans Language: En Journal: Bioanalysis Year: 2014 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google