Molecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residues.

Thompson, Brian R; Houang, Evelyne M; Sham, Yuk Y; Metzger, Joseph M

Thompson, Brian R; Houang, Evelyne M; Sham, Yuk Y; Metzger, Joseph M.

Affiliation

Thompson BR; Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, Minnesota.
Houang EM; Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, Minnesota; Center for Drug Design, University of Minnesota Academic Health Center, Minneapolis, Minnesota.
Sham YY; Center for Drug Design, University of Minnesota Academic Health Center, Minneapolis, Minnesota.
Metzger JM; Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, Minnesota. Electronic address: metzgerj@umn.edu.

Biophys J ; 106(10): 2105-14, 2014 May 20.

Article in En | MEDLINE | ID: mdl-24853739

Subject(s)

Myocytes, Cardiac/metabolism; Troponin I/chemistry; Troponin I/metabolism; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium/metabolism; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Isoforms/chemistry; Protein Isoforms/genetics; Protein Isoforms/metabolism; Protein Structure, Secondary; Rats; Thermodynamics; Transfection; Troponin I/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Troponin I / Myocytes, Cardiac Limits: Animals Language: En Journal: Biophys J Year: 2014 Type: Article

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